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New numbers from the Centers for Disease Control and Prevention show that synthetic opioid use is driving the overdose crisis in the U.S.

A 2,000-foot tower, proposed by developer Christopher Carley and designed by architect Santiago Calatrava, would rise above the lakefront... and give Chicago the nation's two tallest buildings.

NPR's Scott Simon reflects on the work of Chicago-based artist Milton Coronado, who paints murals that memorialize people killed by gun violence.

Lila Hoffa used to struggle to express herself in writing. But her third-grade teacher realized it wasn't a "typical" writing problem and helped Hoffa find a way to make her stories come to life.

Anyone who doesn't want their phone number, email or street address to be found online can ask Google to omit the data from its search results.

The Washington, D.C.-based painter became famous for his Drape works — vibrantly painted pieces of fabric that he hung by clips and could never be presented the same way twice.

A passenger on board the Amtrak train that crashed into a truck and derailed in Missouri on Monday, killing four people, has described the harrowing moment when his carriage rolled.

President Biden said there will be a permanent headquarters in Poland for the U.S. 5th Army Corps. It's one of several ways NATO forces will be beefed up after Russia invaded Ukraine.

The period tracker app Flo is developing an "anonymous mode" in the wake of privacy concerns after the Supreme Court ruled to overturn Roe v. Wade.

The Food and Drug Administration is poised to set a maximum nicotine level in cigarettes and some other tobacco products, looking to make them less addictive and wean smokers off the habit.