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President Bush nominates former investment banker William Donaldson to head the Securities and Exchange Commission. Donaldson's selection comes just a day after the president announced railroad executive John Snow as his choice for treasury secretary. Hear NPR's Jack Speer and Mike McNamee of Business Week.

Barring a last-minute deal, United Airlines is expected to ask a bankruptcy court judge in Chicago to begin the process of terminating labor contracts with its unions. The move could save the airline more than $1 billion. NPR'S David Schaper reports.

Stanford University announces the creation of a new center for stem cell research. In the future, the new center may use a technique known as somatic cell nuclear transfer -- also called therapeutic cloning -- to make embryonic stem cells. NPR's Joe Palca reports.

A North Korean ship is again underway for Yemen with a load of Scud missiles, after being held for two days by U.S. and Spanish forces. The ship's seizure underscores American determination to monitor weapons transfers in the Mideast. Hear from NPR's Tom Gjelten and Georgetown University professor Michael Hudson.

President Bush is set to announce a national plan to vaccinate Americans against smallpox. The plan calls for vaccinating medical and emergency workers early next year, followed by offering the vaccine to the general public in 2004. NPR's Richard Knox reports.

The U.N. nuclear monitorin agency says North Korea is working to restart a nuclear reactor. North Korea accuses the United States of a "hostile policy" that will "backfire." The U.S. State Department says it doesn't want to escalate the situation, but won't be blackmailed. NPR News reports.

The Supreme Court prepares to review several past decisions, including the constitutionality of affirmative action, a Texas anti-sodomy law and Virginia's opposition to cross burning. NPR's Steve Inskeep speaks with NPR's Nina Totenberg.

Iraq puts forth an 11,000-page document answering a U.N. demand to list its arms. Iraqi officials continue to insist that Iraq houses no weapons of mass destruction. What comes next? Hear more from NPR's Scott Simon, NPR's Anne Garrels in Baghdad, and former U.N. arms inspector Terrence Taylor.

A new poll by The Pew Research Center for the People and the Press shows that around the world -- and especially in Muslim nations -- there's been a marked negative shift in peoples' opinion of the United States. NPR's Vicky O'Hara reports, and NPR's Lynn Neary and NPR's Jacki Lyden discuss the poll results with Pew director Andrew Kohut.

Sen. Trent Lott (R-MS) resigns as the Senate's Republican leader following a two-week ordeal over racially divisive remarks. Senators are planning a conference call Monday to select Bill Frist (R-TN) to succeed Lott. Hear NPR's David Welna, NPR's Julie Rovner, NPR's Lynn Neary and Sen. Arlen Specter (R-PA).