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The White House denies it had advance knowledge of Israel's plan to kill Sheik Ahmed Yassin, the spiritual leader of Hamas, which has threatened to retaliate against Israel and the United States. National Security Adviser Condoleezza Rice points to signs of progress in the Mideast peace process, despite Yassin's killing. Hear NPR's Vicky O'Hara.

The Food and Drug Administration says patients on some popular antidepressants should be closely monitored for warning signs of suicide. The agency asked the makers of 10 drugs to add the caution to their product labels. In changing its requirement, the FDA stressed that it is not yet clear that the drugs actually lead to suicide. NPR's Richard Knox reports.

Fighting at Pakistan's Afghan border ceases as tribal elders in the region try to negotiate a resolution to end the holdout of al Qaeda fighters. The area has been under attack by Pakistani troops since Tuesday, when officials determined key Taliban figures -- possibly including Osama bin Laden deputy Ayman al-Zawahiri -- were in the area. Hear NPR's Michael Sullivan.

Shiite militias in the southern Iraqi port city of Basra have been patrolling the streets and cracking down on the sale of music, pornography and alcohol. Many residents now fear criticizing the city's Islamic parties, and British forces occupying the area worry the militias are undermining their activities. NPR's Ivan Watson reports.

Shiite Muslims take steps to ensure their safety as the Ashoura celebration draws to a close. Iraqis establish checkpoints to protect the Kadhimiya mosque, site of one of several bomb attacks Tuesday that left hundreds of Shiite pilgrims dead or wounded. Criticizing U.S. security efforts, Shiites renew calls for an armed militia. Hear NPR's Steve Inskeep and NPR's Ivan Watson.

President George Bush appeals to U.S. allies not to withdraw support from the occupation of Iraq, saying terrorists must not be allowed to influence international policy or leadership. Spain's new prime minister, Jose Luis Rodriguez Zapatero, has called Iraq a "great disaster" and vowed to bring home Spanish troops deployed there. Hear NPR's Don Gonyea.

Former Enron CEO Jeffrey Skilling pleads not guilty as he is indicted on fraud and insider trading charges. Federal prosecutors say Skilling lied about Enron's finances and intentionally deceived investors. Skilling was released after posting a $5 million bail. NPR's Wade Goodwyn reports. Hear NPR's Robert Siegel and law professor John Coffee of Columbia University.

President Bush's long-term plan to send humans back to the moon and on to Mars meets with skepticism in the House Science Committee. Lawmakers Thursday grilled Bush administration officials about the long-term costs of the plan. Among their concerns is that valuable science at NASA will fall victim to an agency budget crunch. NPR's Richard Harris reports.

North Carolina Sen. John Edwards is expected to end his quest for the Democratic presidential bid Wednesday after failing to win a single state contest Tuesday, when more than 1,100 delegates were at stake. Speculation abounds that Edwards may be picked as Sen. John Kerry's running mate in November. NPR's Adam Hochberg reports.

Spain mourns the victims of Thursday's bombings on commuter trains in Madrid that killed nearly 200 people and wounded more than 1,400 others. Spanish officials still suspect the Basque separatist group ETA is to blame. But they are also investigating several clues that suggest al Qaeda may have been involved. Hear NPR's Bob Edwards, reporter Jerome Socolovsky and terrorism analyst Charles Shoebridge.